Ontology highlight
ABSTRACT:
SUBMITTER: Li N
PROVIDER: S-EPMC2858905 | biostudies-other | 2010 Feb
REPOSITORIES: biostudies-other
Li Nan N Kelsh Robert N RN Croucher Peter P Roehl Henry H HH
Development (Cambridge, England) 20100201 3
Although the regulation of osteoblast and adipocyte differentiation from mesenchymal stem cells has been studied for some time, very little is known about what regulates their appearance in discrete regions of the embryo. Here we show that, as in other vertebrates, zebrafish osteoblasts and adipocytes originate in part from cephalic neural crest (CNC) precursors. We investigated the roles that the retinoic acid (RA) and Peroxisome proliferator-activated receptor gamma (Pparg) pathways play in vi ...[more]