Ontology highlight
ABSTRACT:
SUBMITTER: Drobic B
PROVIDER: S-EPMC2879512 | biostudies-other | 2010 Jun
REPOSITORIES: biostudies-other
Drobic Bojan B Pérez-Cadahía Beatriz B Yu Jenny J Kung Sam Kam-Pun SK Davie James R JR
Nucleic acids research 20100203 10
Upon activation of the ERK and p38 MAPK pathways, the MSK1/2-mediated nucleosomal response, including H3 phosphorylation at serine 28 or 10, is coupled with the induction of immediate-early (IE) gene transcription. The outcome of this response, varying with the stimuli and cellular contexts, ranges from neoplastic transformation to neuronal synaptic plasticity. Here, we used sequential co-immunoprecipitation assays and sequential chromatin immunoprecipitation (ChIP) assays on mouse fibroblast 10 ...[more]