Ontology highlight
ABSTRACT:
SUBMITTER: Cinque P
PROVIDER: S-EPMC2919371 | biostudies-other | 2009 Oct
REPOSITORIES: biostudies-other
Cinque Paola P Koralnik Igor J IJ Gerevini Simonetta S Miro Jose M JM Price Richard W RW
The Lancet. Infectious diseases 20091001 10
Progressive multifocal leukoencephalopathy is caused by the JC polyomavirus (JCV) and is one of the most feared complications of HIV-1 infection. Unlike other opportunistic infections, this disease can present when CD4 counts are higher than those associated with AIDS and when patients are receiving combined antiretroviral therapy, either shortly after starting or, more rarely, during long term successful treatment. Clinical suspicion of the disease is typically when MRI shows focal neurological ...[more]