Ontology highlight
ABSTRACT:
SUBMITTER: Lehmann U
PROVIDER: S-EPMC2926161 | biostudies-other | 2010 Oct
REPOSITORIES: biostudies-other
Lehmann Ute U Heuss Neal D ND McPherson Scott W SW Roehrich Heidi H Gregerson Dale S DS
Neurobiology of disease 20100523 1
The presence and activity of dendritic cells (DC) in retina is controversial, as these cells are difficult to identify in retina due to limited markers and sparse numbers. Transgenic mice that express green fluorescent protein (GFP) on the CD11c promoter to label DC allowed the visualization and quantification of retinal DC. Two retina injury models, the optic nerve crush (ONC) and light injury, were used to study their injury response. Many GFP(+) DC were tightly associated with retinal ganglio ...[more]