Unknown

Dataset Information

0

Synaptic plasticity controls sensory responses through frequency-dependent gamma oscillation resonance.


ABSTRACT: Synchronized gamma frequency oscillations in neural networks are thought to be important to sensory information processing, and their effects have been intensively studied. Here we describe a mechanism by which the nervous system can readily control gamma oscillation effects, depending selectively on visual stimuli. Using a model neural network simulation, we found that sensory response in the primary visual cortex is significantly modulated by the resonance between "spontaneous" and "stimulus-driven" oscillations. This gamma resonance can be precisely controlled by the synaptic plasticity of thalamocortical connections, and cortical response is regulated differentially according to the resonance condition. The mechanism produces a selective synchronization between the afferent and downstream neural population. Our simulation results explain experimental observations such as stimulus-dependent synchronization between the thalamus and the cortex at different oscillation frequencies. The model generally shows how sensory information can be selectively routed depending on its frequency components.

SUBMITTER: Paik SB 

PROVIDER: S-EPMC2936516 | biostudies-other | 2010

REPOSITORIES: biostudies-other

altmetric image

Publications

Synaptic plasticity controls sensory responses through frequency-dependent gamma oscillation resonance.

Paik Se-Bum SB   Glaser Donald A DA  

PLoS computational biology 20100909 9


Synchronized gamma frequency oscillations in neural networks are thought to be important to sensory information processing, and their effects have been intensively studied. Here we describe a mechanism by which the nervous system can readily control gamma oscillation effects, depending selectively on visual stimuli. Using a model neural network simulation, we found that sensory response in the primary visual cortex is significantly modulated by the resonance between "spontaneous" and "stimulus-d  ...[more]

Similar Datasets

| S-EPMC3655711 | biostudies-literature
| S-EPMC10830109 | biostudies-literature
| S-EPMC3680733 | biostudies-literature
| S-EPMC2702525 | biostudies-literature
| S-EPMC3206644 | biostudies-literature
| S-EPMC2843436 | biostudies-literature
| S-EPMC4525052 | biostudies-literature
| S-EPMC4754636 | biostudies-literature
| S-EPMC8500065 | biostudies-literature
| S-EPMC4527691 | biostudies-literature