Ontology highlight
ABSTRACT:
SUBMITTER: Freeman AK
PROVIDER: S-EPMC2954851 | biostudies-other | 2010 Sep
REPOSITORIES: biostudies-other
Freeman Alyson K AK Monteiro Alvaro Na AN
Cell communication and signaling : CCS 20100922
In the last fifteen years, rapid progress has been made in delineating the cellular response to DNA damage. The DNA damage response network is composed of a large number of proteins with different functions that detect and signal the presence of DNA damage in order to coordinate DNA repair with a variety of cellular processes, notably cell cycle progression. This signal, which radiates from the chromatin template, is driven primarily by phosphorylation events, mainly on serine and threonine resi ...[more]