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(11R,13R)-13-(Tetra-lin-1-ylamino)-4,5-ep-oxy-11,13-dihydro-costunolide.

ABSTRACT: THE TITLE COMPOUND [SYSTEMATIC NAME: (12R)-4,8-dimethyl-12-[(1'R)-1',2',3',4'-tetrahydro-1'-naphthyl)aminomethyl]-3,14-dioxatricyclo[9.3.0.0(2,4)]tetradec-7-en-13-one}, C(25)H(33)NO(3), was formed from the reaction of (1R)-1-amino-tetra-lin with parthenolide in methano-lic solution. X-ray crystal structure analysis determined that the configuration of the new chiral center in the title compound was R.

SUBMITTER: Nasim S

PROVIDER: S-EPMC2960798 | biostudies-other | 2008

REPOSITORIES: biostudies-other

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(11R,13R)-13-(Tetra-lin-1-ylamino)-4,5-ep-oxy-11,13-dihydro-costunolide.

Nasim Shama S Parkin Sean S Crooks Peter A PA

Acta crystallographica. Section E, Structure reports online 20080229 Pt 3

THE TITLE COMPOUND [SYSTEMATIC NAME: (12R)-4,8-dimethyl-12-[(1'R)-1',2',3',4'-tetrahydro-1'-naphthyl)aminomethyl]-3,14-dioxatricyclo[9.3.0.0(2,4)]tetradec-7-en-13-one}, C(25)H(33)NO(3), was formed from the reaction of (1R)-1-amino-tetra-lin with parthenolide in methano-lic solution. X-ray crystal structure analysis determined that the configuration of the new chiral center in the title compound was R. ...[more]

PMID: 21201970

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(11R)-13-[2-(4-Hydroxy-phen-yl)ethyl-amino]-4,5-ep-oxy-11,13-dihydro-costunolide monohydrate.

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