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(4R,5R,6S,7R,8S,9R,10S,13S)-7,8?-Epoxy-momilactone-A.

ABSTRACT: The title compound, C(20)H(26)O(4), was extracted from Leucas Urticifolia, a wild Lamiaceae herb distributed in the Punjab, Baluchistan, Sindh and the Rajputana desert of Pakistan. The plant is utilized for various medicinal applications by the local community. The title compound is based on the pimarane-diterpene skeleton. The mol-ecule exhibits an ep-oxy ring fused to momilactone-A, leading to a penta-cyclic mol-ecular structure. The absolute configuration was assigned by comparison with the crystal structure of momilactone, but needs further verification. The crystal structure is governed by four inter-molecular hydrogen-bond inter-actions of the C-H?O type.

SUBMITTER: Shabnam Habib R

PROVIDER: S-EPMC2961202 | biostudies-other | 2008

REPOSITORIES: biostudies-other

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(4R,5R,6S,7R,8S,9R,10S,13S)-7,8β-Epoxy-momilactone-A.

Shabnam Habib Rana R Jamshaid Muhammad M Tahir M Nawaz MN Khan Tahir Javed TJ Khan Islam Ullah IU

Acta crystallographica. Section E, Structure reports online 20080423 Pt 5

The title compound, C(20)H(26)O(4), was extracted from Leucas Urticifolia, a wild Lamiaceae herb distributed in the Punjab, Baluchistan, Sindh and the Rajputana desert of Pakistan. The plant is utilized for various medicinal applications by the local community. The title compound is based on the pimarane-diterpene skeleton. The mol-ecule exhibits an ep-oxy ring fused to momilactone-A, leading to a penta-cyclic mol-ecular structure. The absolute configuration was assigned by comparison with the c ...[more]

PMID: 21202375

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