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2-(Tricyclo[3.3.1.1]dec-2-ylamino)ethanol hemihydrate.

ABSTRACT: The title adamantane derivative, C(12)H(21)NO·0.5H(2)O, was synthesized as part of an investigation into the biological activities of cage amino-alcohol compounds as potential anti-tuberculosis agents. The structure displays inter-molecular O-H?N, N-H?O, O-H?O hydrogen bonding and a layered packing structure with distinct hydro-philic and hydro-phobic regions. The water molecule lies on a twofold rotation axis.

SUBMITTER: Boyle GA

PROVIDER: S-EPMC2961807 | biostudies-other | 2008

REPOSITORIES: biostudies-other

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2-(Tricyclo[3.3.1.1]dec-2-ylamino)ethanol hemihydrate.

Boyle Grant A GA Govender Thavendran T Kruger Hendrik G HG Onajole Oluseye K OK

Acta crystallographica. Section E, Structure reports online 20080607 Pt 7

The title adamantane derivative, C(12)H(21)NO·0.5H(2)O, was synthesized as part of an investigation into the biological activities of cage amino-alcohol compounds as potential anti-tuberculosis agents. The structure displays inter-molecular O-H⋯N, N-H⋯O, O-H⋯O hydrogen bonding and a layered packing structure with distinct hydro-philic and hydro-phobic regions. The water molecule lies on a twofold rotation axis. ...[more]

PMID: 21202865

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