Ontology highlight
ABSTRACT:
SUBMITTER: Tomassini JE
PROVIDER: S-EPMC297524 | biostudies-other | 1989 Jul
REPOSITORIES: biostudies-other
Proceedings of the National Academy of Sciences of the United States of America 19890701 13
A 90-kDa surface glycoprotein was previously isolated and shown to be required for infection by the "major" group of human rhinovirus (HRV) serotypes. In the present work, the amino acid sequence of the receptor protein was obtained from CNBr and tryptic peptides. Using degenerate oligonucleotides predicted from the peptide sequences, we identified four cDNA clones that encode a 3-kilobase mRNA. The clones were ligated, subcloned in a simian virus 40 expression vector, and used to transfect rece ...[more]