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The renin angiotensin system and the metabolic syndrome.


ABSTRACT: The renin angiotensin system (RAS) is important for fluid and blood pressure regulation. Recent studies suggest that an overactive RAS is involved in the metabolic syndrome. This article discusses recent advances on how genetic alteration of the RAS affects cardiovascular and metabolic phenotypes, with a special emphasis on the potential role of angiotensin-independent effects of renin.

SUBMITTER: Wang CH 

PROVIDER: S-EPMC2995894 | biostudies-other | 2010

REPOSITORIES: biostudies-other

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The renin angiotensin system and the metabolic syndrome.

Wang Chih-Hong CH   Li Feng F   Takahashi Nobuyuki N  

The open hypertension journal 20100101


The renin angiotensin system (RAS) is important for fluid and blood pressure regulation. Recent studies suggest that an overactive RAS is involved in the metabolic syndrome. This article discusses recent advances on how genetic alteration of the RAS affects cardiovascular and metabolic phenotypes, with a special emphasis on the potential role of angiotensin-independent effects of renin. ...[more]

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