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DNA tunneling detector embedded in a nanopore.

ABSTRACT: We report on the fabrication and characterization of a DNA nanopore detector with integrated tunneling electrodes. Functional tunneling devices were identified by tunneling spectroscopy in different solvents and then used in proof-of-principle experiments demonstrating, for the first time, concurrent tunneling detection and ionic current detection of DNA molecules in a nanopore platform. This is an important step toward ultrafast DNA sequencing by tunneling.

SUBMITTER: Ivanov AP

PROVIDER: S-EPMC3020087 | biostudies-other | 2011 Jan

REPOSITORIES: biostudies-other

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DNA tunneling detector embedded in a nanopore.

Ivanov Aleksandar P AP Instuli Emanuele E McGilvery Catriona M CM Baldwin Geoff G McComb David W DW Albrecht Tim T Edel Joshua B JB

Nano letters 20101206 1

We report on the fabrication and characterization of a DNA nanopore detector with integrated tunneling electrodes. Functional tunneling devices were identified by tunneling spectroscopy in different solvents and then used in proof-of-principle experiments demonstrating, for the first time, concurrent tunneling detection and ionic current detection of DNA molecules in a nanopore platform. This is an important step toward ultrafast DNA sequencing by tunneling. ...[more]

PMID: 21133389

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