Ontology highlight
ABSTRACT:
SUBMITTER: Schroth GP
PROVIDER: S-EPMC306972 | biostudies-other | 1995 Jun
REPOSITORIES: biostudies-other
Nucleic acids research 19950601 11
We have used computer-assisted methods to search large amounts of the human, yeast and Escherichia coli genomes for inverted repeat (IR) and mirror repeat (MR) DNA sequence patterns. In highly supercoiled DNA some IRs can form cruciforms, while some MRs can form intramolecular triplexes, or H-DNA. We find that total IR and MR sequences are highly enriched in both eukaryotic genomes. In E. coli, however, only total IRs are enriched, while total MRs only occur as frequently as in random sequence D ...[more]