Ontology highlight
ABSTRACT:
SUBMITTER: Molnar AO
PROVIDER: S-EPMC3083315 | biostudies-other | 2011 May
REPOSITORIES: biostudies-other
Molnar Amber O AO Coca Steven G SG Devereaux Phillip J PJ Jain Arsh K AK Kitchlu Abhijat A Luo Jin J Parikh Chirag R CR Paterson J Michael JM Siddiqui Nausheen N Wald Ron R Walsh Michael M Garg Amit X AX
Journal of the American Society of Nephrology : JASN 20110414 5
Statins abrogate ischemic renal injury in animal studies but whether they are renoprotective in humans is unknown. We conducted a population-based retrospective cohort study that included 213,347 older patients who underwent major elective surgery in the province of Ontario, Canada from 1995 to 2008. During the first 14 postoperative days, 1.9% (4020 patients), developed acute kidney injury and 0.5% (1173 patients), required acute dialysis. The 30-day mortality rate was 2.8% (5974 patients). Pri ...[more]