Cloning and molecular characterization of a novel chromosome specific centromere sequence of Chinese hamster.
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ABSTRACT:
SUBMITTER: Fatyol K
PROVIDER: S-EPMC308354 | biostudies-other | 1994 Sep
REPOSITORIES: biostudies-other
Publications
Cloning and molecular characterization of a novel chromosome specific centromere sequence of Chinese hamster.
Fátyol K K Cserpán I I Praznovszky T T Keresö J J Hadlaczky G G
Nucleic acids research 19940901 18
We isolated and characterized the first chromosome-specific satellite DNA (HC2sat) of Chinese hamster. This novel satellite was localized to the pericentric region of hamster chromosome 2. The 2.8 kb long repeat unit of HC2sat was identified and two such units were sequenced. Extended short range periodicity could not be revealed in repeat units. These elements are amongst the largest satellite repeat units reported from mammals to date. HC2sat is a major constituent of the pericentric region of ...[more]
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