Ontology highlight
ABSTRACT:
SUBMITTER: Rodriguez-Diaz R
PROVIDER: S-EPMC3135265 | biostudies-other | 2011 Jul
REPOSITORIES: biostudies-other
Rodriguez-Diaz Rayner R Abdulreda Midhat H MH Formoso Alexander L AL Gans Itai I Ricordi Camillo C Berggren Per-Olof PO Caicedo Alejandro A
Cell metabolism 20110701 1
The autonomic nervous system regulates hormone secretion from the endocrine pancreas, the islets of Langerhans, thus impacting glucose metabolism. The parasympathetic and sympathetic nerves innervate the pancreatic islet, but the precise innervation patterns are unknown, particularly in human. Here we demonstrate that the innervation of human islets is different from that of mouse islets and does not conform to existing models of autonomic control of islet function. By visualizing axons in three ...[more]