Who's the Boss? Patterns of Control in Adolescents' Sibling Relationships.
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ABSTRACT:
SUBMITTER: Tucker CJ
PROVIDER: S-EPMC3157954 | biostudies-other | 2010 Dec
REPOSITORIES: biostudies-other
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Project description:Background:Good sibling relationships in adulthood are known to be a protective factor for mental health. The quality of these relationships is influence by the sibship's inherent characteristics (e.g., birth order, number of brothers and sisters, sex composition, age gaps). The present study explored whether these same determinants can help to explain how individuals experience their relationship with a sibling who has been diagnosed with schizophrenia. Method:A total of 374 adults completed the Adult Sibling Relationship Questionnaire, a scale that probes the quality of these relationships on three dimensions: warmth, conflict, and rivalry. We also collected sociodemographic data and information about family structure from each of the participants. Participants were divided into two matched groups: nonclinical sibling group (n = 187) or schizophrenia sibling group (n = 187). Regression analyses were conducted to extract possible predictors of sibling relationship quality for each group. Further regression analyses then focused exclusively on relationships with an ill sibling, in order to study the role of disease-related variables in explaining each of the three dimensions. Results:Results showed that sociodemographic and family structure data explained a significant proportion of variance in the sibling relationship, but solely for nonclinical siblings. When participants had a sibling with schizophrenia, we found that disease-related variables (symptom severity, frequency of treatment) also had to be included to predict the conflict dimension. Conclusions:Our results suggest that feelings of conflict experienced by the schizophrenia sibling group were fueled by the symptoms the ill person displayed. Healthy brothers and sisters probably have only a poor understanding of these symptoms. This could be improved by supporting them and helping them learn more about the disease. Future research will have to prove that providing such support for siblings does indeed improve the quality of their sibling relationships and, by so doing, enhance the wellbeing of both members of a sibling dyad.
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Project description:Researchers have documented associations between family relationships and a variety of well-being outcomes. Yet, sibling relationships, the longest lasting relationships in most people's lives, have received very little research attention beyond young adulthood. The goals of the current study were to: provide descriptive information about sibling relationships in later adulthood, investigate predictors of individual differences in sibling relationship quality, and examine associations among sibling relationship quality, loneliness, and well-being in later adulthood. The sample included 608 older adults (329 men, 279 women) who were 64.6 years old (SD = 4.58) on average. Participants provided self-report data about their relationships and well-being. Results showed that older adults reported high levels of sibling warmth and low levels of sibling conflict and parental favoritism. Sister-sister pairs had warmer sibling relationships than other gender-compositions. Sibling conflict and parental favoritism were positively associated with symptoms of depression, anxiety, hostility, and loneliness. Sibling warmth was negatively associated with loneliness. Loneliness partially mediated the associations between sibling relationship quality and well-being. Results from this study highlight the importance of sibling relationships in older adults' health and well-being. (PsycINFO Database Record (c) 2020 APA, all rights reserved).
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Project description:ObjectiveTo compare the occurrence of injuries in adolescents with childhood-onset epilepsy and matched sibling controls.Study designRetrospective case-control lifetime injury assessments were obtained from a community-based cohort of adolescents with childhood-onset epilepsy diagnosed 9 years earlier and their siblings. The children with epilepsy (n = 501; mean age, 15.3 years) included those with complicated (abnormal neurologic examination or IQ <80; n = 133) and uncomplicated (normal neurologic examination and IQ ?80; n = 368) epilepsy. Children with uncomplicated epilepsy were matched to sibling controls (n = 210 pairs). The children reported whether or not they had ever (before and after epilepsy diagnosis) experienced injuries "serious enough to require medical attention" and if so, the type of treatment required.ResultsAlmost one-half (49.1%) of the children with epilepsy experienced injury, of whom 8.9% required surgery/hospitalization and 17.1% had injury related to a seizure. Fewer children with uncomplicated epilepsy had seizure-related injuries versus those with complicated epilepsy (13.6% vs 27.4%; P ? .01). The proportion of children with epilepsy with any injury by type (not mutually exclusive) were: 25.2% with fractures (n = 126); 24.4% with head injuries (n = 122); 10.2% with other injuries (n = 51); 8.4% with dental injuries (n = 42); and 8% with burns/scalds (n = 40). A similar proportion of children with uncomplicated epilepsy experienced any injury (overall and by type) compared to matched sibling controls, with the exception that more children with uncomplicated epilepsy had head injuries (30.0% vs 19.5%; P < .02).ConclusionWith the exception of head injuries, we found no evidence of an increased risk of injury in a representative cohort of children with epilepsy compared with matched sibling controls. This finding may reflect the fact that the sample was not biased to more severe cases, or that safety precautions to prevent injury were widely used.
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Project description:In cells the quality of newly synthesized proteins is monitored in regard to proper folding and correct assembly in the early secretory pathway, the cytosol and the nucleoplasm. Proteins recognized as non-native in the ER will be removed and degraded by a process termed ERAD. ERAD of aberrant proteins is accompanied by various changes of cellular organelles and results in protein folding diseases. This review focuses on how the immunocytochemical labeling and electron microscopic analyses have helped to disclose the in situ subcellular distribution pattern of some of the key machinery proteins of the cellular protein quality control, the organelle changes due to the presence of misfolded proteins, and the efficiency of synthetic chaperones to rescue disease-causing trafficking defects of aberrant proteins.
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Project description:ObjectiveTo study the racial and socioeconomic characteristics of women seeking fertility care in a state with mandated insurance coverage for fertility testing and treatment.DesignCross-sectional, self-administered survey.SettingAcademic fertility center in Illinois.PatientsOf 5,000 consecutive fertility care patients, 1,460 completed the survey and were included in the study sample.InterventionsNone.Main outcome measuresDetails about demographic characteristics and health care access on the basis of patient race/ethnicity and socioeconomic status.ResultsThe mean age of participants was 36.1 years; 75.5% were White, 10.2% Asian, 7.3% Black, 5.7% Latinx, and 1.3% Other. Most women had a bachelor's (35.5%) or master's degree (40.5%) and an annual household income of >$100,000 (81.5%). Black and Hispanic women traveled twice as far (median 10 miles) as White and Asian women (median 5 miles for both) for treatment. Black women (14.7%) were more likely to report that their race was a barrier to getting fertility treatment compared with White (0.0%), Hispanic (5.1%), and Asian (5.4%) women. Black and Hispanic women were approximately twice as likely to report income level (26.5% and 20.3%, respectively) and weight (7.8% and 8.9%, respectively) as barriers compared with White and Asian respondents.ConclusionsSignificant racial and socioeconomic disparities exist among fertility patients accessing care. Beyond providing all Americans with health insurance that covers fertility treatment, further research in the general population is needed to understand the complex social, cultural, racial, and economic factors that prohibit many individuals from accessing needed fertility care.
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Project description:Finding ways to protect youth from maladjustment during adolescence and young adulthood is important, and youth of Mexican descent are key targets for such efforts given that they experience higher rates of depressive symptoms, risky behaviors, and sexual risk behaviors compared to youth from other ethnic/racial groups. Using a sample of younger (Mage Time 1 = 12.77 years) and older (Mage Time 1 = 15.70 years) siblings from an 8-year longitudinal study of 246 Mexican-origin families, we conducted path analyses to test whether older siblings' reports of sibling intimacy predicted younger siblings' later positive values and adjustment problems controlling for prior adjustment and maternal and paternal warmth. Additionally, we tested whether younger siblings' familism values moderated and their positive values mediated the sibling intimacy to adjustment problem linkages. Findings revealed that sibling intimacy in early adolescence predicted younger siblings' adjustment problems in young adulthood via their positive values in later adolescence, but only for younger siblings with strong familism values. This study highlights the importance of examining promotive factors, such as positive relationship qualities and familism values, and how positive values protect against problems in young adulthood. Results also have practical implications for prevention programs including the utility of promoting positive sibling relationships and values. (PsycInfo Database Record (c) 2021 APA, all rights reserved).
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