Ontology highlight
ABSTRACT:
SUBMITTER: El-Osta HE
PROVIDER: S-EPMC3228122 | biostudies-other | 2011
REPOSITORIES: biostudies-other
The oncologist 20110325 4
Castleman's disease is a rare lymphoproliferative disorder in which there has been recent progress in elucidating underlying mechanisms with potential therapeutic implications. Unicentric Castleman's disease is an indolent condition that is often treated with local approaches. In contrast, patients with multicentric Castleman's disease (MCD) have a less favorable prognosis and require systemic treatment. Cytotoxic chemotherapy, with its attendant risk for toxicity, has been widely used to treat ...[more]