Ontology highlight
ABSTRACT:
SUBMITTER: Voon PJ
PROVIDER: S-EPMC3256457 | biostudies-other | 2010 Sep
REPOSITORIES: biostudies-other
Voon Pei-Jye PJ Chul Cho Byoung B Yeo Wee-Lee WL Soo Ross A RA
Journal of thoracic disease 20100901 3
The epidermal growth factor receptor tyrosine kinase inhibitors (EGFR TKIs) like erlotinib and gefitinib have been extensively studied. Multiple randomized trials have evaluated the role of EGFR TKIs in advanced stage non-small cell lung cancer (NSCLC) as a monotherapy in the first line, or subsequent lines of therapy, and in the first line in the maintenance setting or in combination with chemotherapy. Most of these trials showed positive results in particular for selected patients with specifi ...[more]