Ontology highlight
ABSTRACT:
SUBMITTER: Li X
PROVIDER: S-EPMC3278736 | biostudies-other | 2012 Mar
REPOSITORIES: biostudies-other
Li X X Zhang J J Gao L L McClellan S S Finan M A MA Butler T W TW Owen L B LB Piazza G A GA Xi Yaguang Y
Cell death and differentiation 20111007 3
MicroRNAs (miRNAs) have attracted attention because of their key regulatory functions in many biological events, including differentiation and tumorigenesis. Recent studies have reported the existence of a reciprocal regulatory loop between the family of let-7 miRNAs and an RNA-binding protein, Lin28, both of which have been documented for their important roles during cell differentiation. Hence, using bipotent K562 human leukemia cells and human CD34+ hematopoietic progenitor cells as research ...[more]