Evolutionary conservation of the spliceosomal protein, U2B''.
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ABSTRACT:
SUBMITTER: Simpson GG
PROVIDER: S-EPMC328878 | biostudies-other | 1991 Oct
REPOSITORIES: biostudies-other
Publications
Evolutionary conservation of the spliceosomal protein, U2B''.
Simpson G G GG Vaux P P Clark G G Waugh R R Beggs J D JD Brown J W JW
Nucleic acids research 19911001 19
U1 and U2snRNPs play key roles in pre-mRNA splicing. The interactions between the U1 and U2snRNP-specific proteins, U1A, U2A' and U2B'' and their respective UsnRNAs are of interest both to elucidate their roles in splicing, and as models to study RNA-protein interactions. We have cloned a full-length cDNA, encoding U2B'', from potato. This is the first report of a sequence for a plant UsnRNP protein. The plant U2B'' sequence exhibits extensive similarity with the human U2B'' protein at both the ...[more]
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