Developmentally regulated transporter in Leishmania is encoded by a family of clustered genes.
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ABSTRACT:
SUBMITTER: Stein DA
PROVIDER: S-EPMC330524 | biostudies-other | 1990 Mar
REPOSITORIES: biostudies-other
Publications
Developmentally regulated transporter in Leishmania is encoded by a family of clustered genes.
Stein D A DA Cairns B R BR Landfear S M SM
Nucleic acids research 19900301 6
We have previously cloned a gene for a developmentally regulated transport protein from the trypanosomatid protozoan Leishmania enriettii. We demonstrate here that this transporter is encoded by a single family of tandemly clustered genes containing approximately 8 copies of the 3.6 kilobase repeat unit. Transcriptional mapping defines a contiguous 3.3 kilobase region of the repeat unit that encodes the mRNA. The 5' end of the mature mRNA contains the spliced leader or mini-exon previously ident ...[more]
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