Ontology highlight
ABSTRACT:
SUBMITTER: Piedad JC
PROVIDER: S-EPMC3306931 | biostudies-other | 2012
REPOSITORIES: biostudies-other
Parkinson's disease 20120209
Dopamine agonists such as pramipexole (PPX) have first been proposed as adjunctive treatment to levodopa (L-DOPA) for patients with Parkinson's disease (PD) and then as a monotherapy alternative to alleviate dyskinesia. Treatment with PPX has overall been associated with improvement in parkinsonian symptoms. Although the majority of placebo-controlled studies demonstrated that dyskinesia was more prevalent in the PPX compared to the placebo groups, some studies did not detect any dyskinesia as a ...[more]