Ontology highlight
ABSTRACT:
SUBMITTER: Xu Z
PROVIDER: S-EPMC3311162 | biostudies-other | 2012 Feb
REPOSITORIES: biostudies-other
Xu Zhigang Z Shaw Arthur Y AY Dietrich Justin J Cappelli Alexandra P AP Nichol Gary G Hulme Christopher C
Molecular diversity 20120112 1
Three scaffolds of benzimidazoles, bis-benzimidazoles, and bis-benzimidazole-dihydroquinoxalines were synthesized via Ugi/de-protection/cyclization methodology. Benzimidazole forming ring closure was enabled under microwave irradiation in the presence of 10% TFA/DCE. The methodology demonstrates the utility of 2-(N-Boc-amino)-phenyl-isocyanide for the generation of new molecular diversity. ...[more]