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Differential gene expression after gamma radiation in bis-benzimidazole-treated human glioblastoma using microarray analysis

ABSTRACT: Radiation-induced DNA damage initiates a complex series of overlapping responses responsible for the maintenance of genome integrity. This study reports the expression analysis in response to DNA minor groove binding ligand (DMA-5-(4-methylpiperazin-1-yl)-2-[2’-(3,4-dimethoxyphenyl)-5`-benzimidazolyl] benzimidazole, an analogue of Hoechst 33342), with an emphasis on its ability to afford better protection in cells exposed to ionizing radiation.

ORGANISM(S): Homo sapiens

PROVIDER: GSE30043 | GEO | 2011/08/01

SECONDARY ACCESSION(S): PRJNA144075

REPOSITORIES: GEO

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Molecular mechanism of DNA minor groove binding ligand as a radiation modulator

2011-08-01 | GSE30044 | GEO

Differential gene expression after gamma radiation in bis-benzimidazole-treated human glioblastoma using microarray analysis

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