Ontology highlight
ABSTRACT:
SUBMITTER: Dorer DR
PROVIDER: S-EPMC332228 | biostudies-other | 1990 Sep
REPOSITORIES: biostudies-other
Dorer D R DR Christensen A C AC Johnson D H DH
Nucleic acids research 19900901 18
The Triplo-lethal (Tpl) locus of Drosophila is the only known locus which is lethal when present in three copies rather than the normal two. After recovering a hybrid-dysgenesis-induced mutation of Tpl we used a rapid combination of transposon tagging, chromosome microdissection and PCR to clone the P element that had transposed into the Tpl region. That P element is located within the gene for a new and unique member of the RNA helicase family. This new helicase differs from all others known by ...[more]