Ontology highlight
ABSTRACT:
SUBMITTER: Calderon Villalobos LI
PROVIDER: S-EPMC3331960 | biostudies-other | 2012 Apr
REPOSITORIES: biostudies-other
Nature chemical biology 20120401 5
The plant hormone auxin regulates virtually every aspect of plant growth and development. Auxin acts by binding the F-box protein transport inhibitor response 1 (TIR1) and promotes the degradation of the AUXIN/INDOLE-3-ACETIC ACID (Aux/IAA) transcriptional repressors. Here we show that efficient auxin binding requires assembly of an auxin co-receptor complex consisting of TIR1 and an Aux/IAA protein. Heterologous experiments in yeast and quantitative IAA binding assays using purified proteins sh ...[more]