Ontology highlight
ABSTRACT:
SUBMITTER: LeSauter J
PROVIDER: S-EPMC3338757 | biostudies-other | 2012
REPOSITORIES: biostudies-other
LeSauter Joseph J Lambert Christopher M CM Robotham Margaret R MR Model Zina Z Silver Rae R Weaver David R DR
PloS one 20120427 4
Research on the mechanisms underlying circadian rhythmicity and the response of brain and body clocks to environmental and physiological challenges requires assessing levels of circadian clock proteins. Too often, however, it is difficult to acquire antibodies that specifically and reliably label these proteins. Many of these antibodies also lack appropriate validation. The goal of this project was to generate and characterize antibodies against several circadian clock proteins. We examined mice ...[more]