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Sequence and variability of the 5.8S and 26S rRNA genes of Pneumocystis carinii.


ABSTRACT: The sequence of the coding region of the rRNA operon of rat-derived Pneumocystis carinii has been completed, including the genes for 5.8S and 26S rRNA. These genes show homology to the rRNA genes of yeast, and an apparent group I self-splicing intron is present in the 26S rRNA gene. Like a similar intron in the 16S rRNA gene, this intron is in a phylogenetically conserved region. Variation in the 26S rRNA sequence was noted between P. carinii organisms isolated from two different sources.

SUBMITTER: Liu Y 

PROVIDER: S-EPMC334029 | biostudies-other | 1992 Jul

REPOSITORIES: biostudies-other

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Sequence and variability of the 5.8S and 26S rRNA genes of Pneumocystis carinii.

Liu Y Y   Rocourt M M   Pan S S   Liu C C   Leibowitz M J MJ  

Nucleic acids research 19920701 14


The sequence of the coding region of the rRNA operon of rat-derived Pneumocystis carinii has been completed, including the genes for 5.8S and 26S rRNA. These genes show homology to the rRNA genes of yeast, and an apparent group I self-splicing intron is present in the 26S rRNA gene. Like a similar intron in the 16S rRNA gene, this intron is in a phylogenetically conserved region. Variation in the 26S rRNA sequence was noted between P. carinii organisms isolated from two different sources. ...[more]

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