Ontology highlight
ABSTRACT:
SUBMITTER: Leite MI
PROVIDER: S-EPMC3348852 | biostudies-other | 2012 May
REPOSITORIES: biostudies-other
Leite M I MI Coutinho E E Lana-Peixoto M M Apostolos S S Waters P P Sato D D Melamud L L Marta M M Graham A A Spillane J J Villa A M AM Callegaro D D Santos E E da Silva A Martins AM Jarius S S Howard R R Nakashima I I Giovannoni G G Buckley C C Hilton-Jones D D Vincent A A Palace J J
Neurology 20120502 20
<h4>Objective</h4>To describe 16 patients with a coincidence of 2 rare diseases: aquaporin-4 antibody (AQP4-Ab)-mediated neuromyelitis optica spectrum disorder (AQP4-NMOSD) and acetylcholine receptor antibody (AChR-Ab)-mediated myasthenia gravis (AChR-MG).<h4>Methods</h4>The clinical details and antibody results of 16 patients with AChR-MG and AQP4-NMOSD were analyzed retrospectively.<h4>Results</h4>All had early-onset AChR-MG, the majority with mild generalized disease, and a high proportion ac ...[more]