Ontology highlight
ABSTRACT:
SUBMITTER: Acampora D
PROVIDER: S-EPMC335308 | biostudies-other | 1989 Dec
REPOSITORIES: biostudies-other
Acampora D D D'Esposito M M Faiella A A Pannese M M Migliaccio E E Morelli F F Stornaiuolo A A Nigro V V Simeone A A Boncinelli E E
Nucleic acids research 19891201 24
We report the identification of 10 new human homeobox sequences. Altogether, we have isolated and sequenced 30 human homeoboxes clustered in 4 chromosomal regions called HOX loci. HOX1 includes 8 homeoboxes in 90 kb of DNA on chromosome 7. HOX2 includes 9 homeoboxes in 180 kb on chromosome 17. HOX3 contains at least 7 homeoboxes in 160 kb on chromosome 12. Finally, HOX4 includes 6 homeoboxes in 70 kb on chromosome 2. Homeodomains obtained from the conceptual translation of the isolated homeoboxe ...[more]