Unknown

Dataset Information

0

17?H-Periplogenin, a cardiac aglycone from the root bark of Periploca sepium Bunge.


ABSTRACT: The title compound {systematic name: 4-[(3S,5S,8R,9S,10R,13R,14S,17S)-3,5,14-trihy-droxy-10,13-dimethyl-hexa-deca-hydro-1H-cyclo-penta-[a]phenanthren-17-yl]furan-2(5H)-one}, C(23)H(34)O(5), was isolated from the roots of Periploca sepium Bunge, a famous Chinese traditional herbal medicine. The three six-membered rings adopt chair conformations, the cyclo-pentane ring displays an approximate envelope conformation (with the C atom bearing the methyl substituent at the flap) and the five-membered lactone ring adopts an essentially planar [maximum deviation of 0.004?(8)?Å] conformation. In the crystal, mol-ecules are linked into helical chains along [010] by O-H?O hydrogen bonds and weak C-H?O inter-actions. Two intra-molecular O-H?O hydrogen bonds are also present.

SUBMITTER: Zhang YW 

PROVIDER: S-EPMC3379196 | biostudies-other | 2012 Jun

REPOSITORIES: biostudies-other

altmetric image

Publications

17βH-Periplogenin, a cardiac aglycone from the root bark of Periploca sepium Bunge.

Zhang Yu-Wei YW   Bao Yong-Li YL   Wu Yin Y   Yu Chun-Lei CL   Li Yu-Xin YX  

Acta crystallographica. Section E, Structure reports online 20120502 Pt 6


The title compound {systematic name: 4-[(3S,5S,8R,9S,10R,13R,14S,17S)-3,5,14-trihy-droxy-10,13-dimethyl-hexa-deca-hydro-1H-cyclo-penta-[a]phenanthren-17-yl]furan-2(5H)-one}, C(23)H(34)O(5), was isolated from the roots of Periploca sepium Bunge, a famous Chinese traditional herbal medicine. The three six-membered rings adopt chair conformations, the cyclo-pentane ring displays an approximate envelope conformation (with the C atom bearing the methyl substituent at the flap) and the five-membered l  ...[more]

Similar Datasets

| S-EPMC6272825 | biostudies-literature
| S-EPMC7464275 | biostudies-literature
| S-EPMC2471879 | biostudies-literature
| S-EPMC10304121 | biostudies-literature
| S-EPMC2638005 | biostudies-literature
| S-EPMC7554996 | biostudies-literature
| S-EPMC9249669 | biostudies-literature
| S-EPMC3827909 | biostudies-literature
| S-EPMC8720881 | biostudies-literature
| PRJNA1141784 | ENA