Ontology highlight
ABSTRACT:
SUBMITTER: Wu Y
PROVIDER: S-EPMC3424258 | biostudies-other | 2012
REPOSITORIES: biostudies-other
Wu Yanhua Y Jiang Wenjun W Wang Yingming Y Wu Jun J Saiyin Hexige H Qiao Xiaojing X Mei Xinyu X Guo Bin B Fang Xiao X Zhang Lu L Lou Huiling H Wu Chaoqun C Qiao Shouyi S
PloS one 20120821 8
Breast cancer metastasis suppressor 1 (BRMS1) was originally identified as an active metastasis suppressor in human breast cancer. Loss of BRMS1 expression correlates with tumor progression, and BRMS1 suppresses several steps required for tumor metastasis. However, the role of BRMS1 in hepatocellular carcinoma (HCC) remains elusive. In this study, we found that the expression level of BRMS1 was significantly down-regulated in HCC tissues. Expression of BRMS1 in SK-Hep1 cells did not affect cell ...[more]