X-ray imaging of tumor growth in live mice by detecting gold-nanoparticle-loaded cells.
Ontology highlight
ABSTRACT:
SUBMITTER: Chien CC
PROVIDER: S-EPMC3429882 | biostudies-other | 2012
REPOSITORIES: biostudies-other
Publications
X-ray imaging of tumor growth in live mice by detecting gold-nanoparticle-loaded cells.
Chien Chia-Chi CC Chen Hsiang-Hsin HH Lai Sheng-Feng SF Hwu Y Y Petibois Cyril C Yang C S CS Chu Y Y Margaritondo G G
Scientific reports 20120829
We show that sufficient concentrations of gold nanoparticles produced by an original synthesis method in EMT-6 and CT-26 cancer cells make it possible to detect the presence, necrosis and proliferation of such cells after inoculation in live mice. We first demonstrated that the nanoparticles do not interfere with the proliferation process. Then, we observed significant differences in the tumor evolution and the angiogenesis process after shallow and deep inoculation. A direct comparison with pat ...[more]
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