Unknown

Dataset Information

0

Theory of signal and noise in double-gated nanoscale electronic pH sensors.


ABSTRACT: The maximum sensitivity of classical nanowire (NW)-based pH sensors is defined by the Nernst limit of 59 mV/pH. For typical noise levels in ultra-small single-gated nanowire sensors, the signal-to-noise ratio is often not sufficient to resolve pH changes necessary for a broad range of applications. Recently, a new class of double-gated devices was demonstrated to offer apparent "super-Nernstian" response (>59 mV/pH) by amplifying the original pH signal through innovative biasing schemes. However, the pH-sensitivity of these nanoscale devices as a function of biasing configurations, number of electrodes, and signal-to-noise ratio (SNR) remains poorly understood. Even the basic question such as "Do double-gated sensors actually resolve smaller changes in pH compared to conventional single-gated sensors in the presence of various sources of noise?" remains unanswered. In this article, we provide a comprehensive numerical and analytical theory of signal and noise of double-gated pH sensors to conclude that, while the theoretical lower limit of pH-resolution does not improve for double-gated sensors, this new class of sensors does improve the (instrument-limited) pH resolution.

SUBMITTER: Go J 

PROVIDER: S-EPMC3436503 | biostudies-other | 2012 Aug

REPOSITORIES: biostudies-other

Similar Datasets

| S-EPMC3042585 | biostudies-literature
| S-EPMC3144966 | biostudies-other
| S-EPMC7044230 | biostudies-literature
| S-EPMC5666504 | biostudies-literature
| S-EPMC4239864 | biostudies-literature
| S-EPMC9503050 | biostudies-literature
| S-EPMC4304641 | biostudies-literature
| S-EPMC6097920 | biostudies-literature
| S-EPMC10174484 | biostudies-literature
| S-EPMC8339940 | biostudies-literature