Ontology highlight
ABSTRACT:
SUBMITTER: Lallemend F
PROVIDER: S-EPMC3442276 | biostudies-other | 2012 Sep
REPOSITORIES: biostudies-other
Lallemend Francois F Sterzenbach Ulrich U Hadjab-Lallemend Saida S Aquino Jorge B JB Castelo-Branco Goncalo G Sinha Indranil I Villaescusa J Carlos JC Levanon Ditsa D Wang Yiqiao Y Franck Marina C M MC Kharchenko Olga O Adameyko Igor I Linnarsson Sten S Groner Yoram Y Turner Eric E Ernfors Patrik P
The EMBO journal 20120817 18
The formation of functional connectivity in the nervous system is governed by axon guidance that instructs nerve growth and branching during development, implying a similarity between neuronal subtypes in terms of nerve extension. We demonstrate the molecular mechanism of another layer of complexity in vertebrates by defining a transcriptional program underlying growth differences between positionally different neurons. The rate of axon extension of the early subset of embryonic dorsal root gang ...[more]