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Ultra-high cooling rate utilizing thin film evaporation.


ABSTRACT: This research introduces a cell cryopreservation method, which utilizes thin film evaporation and provides an ultra-high cooling rate. The microstructured surface forming the thin film evaporation was fabricated from copper microparticles with an average diameter of 50 μm. Experimental results showed that a cooling rate of approximately 5[Formula: see text]10(4) °C/min was achieved in a temperature range from 10 °C to -187 °C. The current investigation will give birth to a cell cryopreservation method through vitrification with relatively low concentrations of cryoprotectants.

SUBMITTER: Su F 

PROVIDER: S-EPMC3460952 | biostudies-other | 2012 Sep

REPOSITORIES: biostudies-other

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