Ontology highlight
ABSTRACT:
SUBMITTER: Peng F
PROVIDER: S-EPMC3489503 | biostudies-other | 2012 Jan
REPOSITORIES: biostudies-other
Chemical science 20120101 10
Controlled isomerization of the double bond of certain Diels-Alder reactions provides substrates that, upon oxidation, give rise to products whose gross structure corresponds to that of a Robinson annulation. In these cases, the stereochemistry of the Robinson annulation product reflects the fact that the initial combination occurred in a Diels-Alder mode. Using these principles, we have synthesized carissone and cosmosoic acid. In the latter case, our total synthesis raised serious questions as ...[more]