Ontology highlight
ABSTRACT:
SUBMITTER: Petralia RS
PROVIDER: S-EPMC3495249 | biostudies-other | 2012 Dec
REPOSITORIES: biostudies-other
Petralia Ronald S RS Wang Ya-Xian YX Mattson Mark P MP Yao Pamela J PJ
Cerebellum (London, England) 20121201 4
The Sonic hedgehog (Shh) signaling pathway carries out a wide range of biological functions such as patterning of the embryonic neural tube and expansion of cerebellar granule cell precursors. We previously have found that the Shh signaling receptors, Patched1 (Ptch1) and Smoothened (Smo), are expressed in hippocampal neurons of developing and adult rats, suggesting the continued presence of Shh signaling in postmitotic, differentiated neurons. Here, we report that Ptch1 and Smo are present in t ...[more]