Ontology highlight
ABSTRACT:
SUBMITTER: Zingaretti C
PROVIDER: S-EPMC3518104 | biostudies-other | 2012 Dec
REPOSITORIES: biostudies-other
Zingaretti Chiara C Arigò Milena M Cardaci Angela A Moro Monica M Crosti Mariacristina M Sinisi Antonella A Sugliano Elisa E Cheroni Cristina C Marabita Francesco F Nogarotto Renzo R Bonnal Raoul Jean Pierre RJ Marcatili Paolo P Marconi Maurizio M Zignego Annalinda A Muratori Paolo P Invernizzi Pietro P Colombatto Piero P Brunetto Maurizia M Bonino Ferruccio F De Francesco Raffaele R Geginat Jens J Pagani Massimiliano M Muratori Luigi L Abrignani Sergio S Bombaci Mauro M
Molecular & cellular proteomics : MCP 20120920 12
Autoimmune hepatitis (AIH) is an unresolving inflammation of the liver of unknown cause. Diagnosis requires the exclusion of other conditions and the presence of characteristic features such as specific autoantibodies. Presently, these autoantibodies have relatively low sensitivity and specificity and are identified via immunostaining of cells or tissues; therefore, there is a diagnostic need for better and easy-to-assess markers. To identify new AIH-specific autoantigens, we developed a protein ...[more]