Ontology highlight
ABSTRACT:
SUBMITTER: Rabinovitch M
PROVIDER: S-EPMC3533531 | biostudies-other | 2012 Dec
REPOSITORIES: biostudies-other
The Journal of clinical investigation 20121203 12
Recent clinical and experimental studies are redefining the cellular and molecular bases of pulmonary arterial hypertension (PAH). The genetic abnormalities first identified in association with the idiopathic form of PAH--together with a vast increase in our understanding of cell signaling, cell transformation, and cell-cell interactions; gene expression; microRNA processing; and mitochondrial and ion channel function--have helped explain the abnormal response of vascular cells to injury. Experi ...[more]