Ontology highlight
ABSTRACT:
SUBMITTER: Jensen KJ
PROVIDER: S-EPMC3553504 | biostudies-other | 2013 Jan
REPOSITORIES: biostudies-other
Jensen Karin J KJ Garmaroudi Farshid S FS Zhang Jingchun J Lin Jun J Boroomand Seti S Zhang Mary M Luo Zongshu Z Yang Decheng D Luo Honglin H McManus Bruce M BM Janes Kevin A KA
Cell host & microbe 20130116 1
The host response to a virus is determined by intracellular signaling pathways that are modified during infection. These pathways converge as networks and produce interdependent phenotypes, making it difficult to link virus-induced signals and responses at a systems level. Coxsackievirus B3 (CVB3) infection induces death of cardiomyocytes, causing tissue damage and virus dissemination, through incompletely characterized host cell signaling networks. We built a statistical model that quantitative ...[more]