Ontology highlight
ABSTRACT:
SUBMITTER: Ramachandran V
PROVIDER: S-EPMC3572760 | biostudies-other | 2013
REPOSITORIES: biostudies-other
Ramachandran Vasanthi V Singh Ragini R Yang Xiaoyu X Tunduguru Ragadeepthi R Mohapatra Subrat S Khandelwal Swati S Patel Sanjana S Datta Santanu S
Advances and applications in bioinformatics and chemistry : AABC 20130207
The equity of a drug target is principally evaluated by its genetic vulnerability with tools ranging from antisense- and microRNA-driven knockdowns to induced expression of the target protein. In order to upgrade the process of antibacterial target identification and discern its most effective type of inhibition, an in silico toolbox that evaluates its genetic and chemical vulnerability leading either to stasis or cidal outcome was constructed and validated. By precise simulation and careful exp ...[more]