Ontology highlight
ABSTRACT:
SUBMITTER: Wang T
PROVIDER: S-EPMC3583528 | biostudies-other | 2012 Oct
REPOSITORIES: biostudies-other
Oncology reports 20120806 4
Glioma cells are characterized by their invasiveness and resistance to conventional therapeutics. The downregulation of human telomerase reverse transcriptase (hTERT) can lead to decreased cell proliferation and/or the induction of apoptotic cell death in cancer cells but has rarely been reported in glioma cells. Here, we assessed the effect of the silencing of the hTERT gene on cell apoptosis and its possible molecular mechanism in T98 ...[more]