Ontology highlight
ABSTRACT:
SUBMITTER: Dai N
PROVIDER: S-EPMC3589448 | biostudies-other | 2013
REPOSITORIES: biostudies-other
Dai Nan N Cao Xiao-Jing XJ Li Meng-Xia MX Qing Yi Y Liao Ling L Lu Xian-Feng XF Zhang Shi-Heng SH Li Zheng Z Yang Yu-Xin YX Wang Dong D
PloS one 20130305 3
Apurinic/apyrimidinic endonuclease 1 (APE1), which has the dual functions of both DNA repair and redox activity, has been reported to be highly expressed in non-small cell lung cancer (NSCLC), and this appears to be a characteristic related to chemotherapy resistance. In this study, we identified serum APE1 autoantibodies (APE1-AAbs) in NSCLC patients and healthy controls by immunoblotting and investigated the expression of APE1-AAbs by indirect ELISA from the serum of 292 NSCLC patients and 300 ...[more]