Ontology highlight
ABSTRACT:
SUBMITTER: Okazaki S
PROVIDER: S-EPMC359452 | biostudies-other | 1993 Mar
REPOSITORIES: biostudies-other
Okazaki S S Tsuchida K K Maekawa H H Ishikawa H H Fujiwara H H
Molecular and cellular biology 19930301 3
A pentanucleotide repetitive sequence, (TTAGG)n, has been isolated from a silkworm genomic library, using cross-hybridization with a (TTNGGG)5 sequence, which is conserved among most eukaryotic telomeres. Both fluorescent in situ hybridization and Bal 31 exonuclease experiments revealed major clusters of (TTAGG)n at the telomeres of all Bombyx chromosomes. To determine the evolutionary origin of this sequence, two types of telomeric sequence, (TTAGG)5 and a hexanucleotide repetitive sequence, (T ...[more]