Ontology highlight
ABSTRACT:
SUBMITTER: Chang YC
PROVIDER: S-EPMC3651482 | biostudies-other | 2013 May
REPOSITORIES: biostudies-other
Chang Yu-Chiuan YC Jang Anna C-C AC Lin Cheng-Han CH Montell Denise J DJ
Proceedings of the National Academy of Sciences of the United States of America 20130422 19
Asymmetric division of stem cells results in both self-renewal and differentiation of daughters. Understanding the molecules and mechanisms that govern differentiation of specific cell types from adult tissue stem cells is a major challenge in developmental biology and regenerative medicine. Drosophila follicle stem cells (FSCs) represent an excellent model system to study adult stem cell behavior; however, the earliest stages of follicle cell differentiation remain largely mysterious. Here we i ...[more]