Ontology highlight
ABSTRACT:
SUBMITTER: Ikeda S
PROVIDER: S-EPMC3654726 | biostudies-other | 2013 Jan-Mar
REPOSITORIES: biostudies-other
Ikeda Shuji S Yanagisawa Hiroyuki H Yuki Mizue M Okamoto Akimitsu A
Artificial DNA, PNA & XNA 20130101 1
Fluorescent probes for the detection of a double-stranded DNA were prepared by labeling a triplex-forming DNA oligonucleotide with a thiazole orange (TO) dimer unit. They belong to ECHO (exciton-controlled hybridization-sensitive fluorescent oligonucleotide) probes which we have previously reported. The excitonic interaction between the two TO molecules was expected to effectively suppress the background fluorescence of the probes. The applicability of the ECHO probes for the detection of double ...[more]