Ontology highlight
ABSTRACT:
SUBMITTER: Michod D
PROVIDER: S-EPMC3657165 | biostudies-other | 2012 Apr
REPOSITORIES: biostudies-other
Michod David D Bartesaghi Stefano S Khelifi Amel A Bellodi Cristian C Berliocchi Laura L Nicotera Pierluigi P Salomoni Paolo P
Neuron 20120401 1
Activity-dependent modifications of chromatin are believed to contribute to dramatic changes in neuronal circuitry. The mechanisms underlying these modifications are not fully understood. The histone variant H3.3 is incorporated in a replication-independent manner into different regions of the genome, including gene regulatory elements. It is presently unknown whether H3.3 deposition is involved in neuronal activity-dependent events. Here, we analyze the role of the histone chaperone DAXX in the ...[more]