Ontology highlight
ABSTRACT:
SUBMITTER: Li N
PROVIDER: S-EPMC3677567 | biostudies-other | 2013 Feb
REPOSITORIES: biostudies-other
Future microbiology 20130201 2
<h4>Aim</h4>In this study, we investigate whether pH (low) insertion peptide (pHLIP) can target regions of lung injury associated with influenza infection.<h4>Materials & methods</h4>Fluorophore-conjugated pHLIP was injected intraperitoneally into mice infected with a sublethal dose of H1N1 influenza and visualized histologically.<h4>Results</h4>pHLIP specifically targeted inflamed lung tissues of infected mice in the later stages of disease and at sites where alveolar type I and type II cells w ...[more]